heart rate — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T2535	Ivabradine hydrochloride	S 16257-2,Ivabradine HCl	Adrenergic Receptor
	Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat...		Adrenergic Receptor
T23535L	Xanthine amine congener trihydrochloride	Xanthine amine congener trihydrochloride (96865-92-8 Free base)	Adenosine Receptor
	Xanthine amine congener trihydrochloride is a potent adenosine antagonist that reverses the reduction in urine flow, sodium excretion and heart rate produced by the adenosine agonist, N6-cyclohexyladenosine.		Adenosine Receptor
T28748	Selodenoson	RG14202,DTI0009,DTI-0009,RG-14202,DT-009,DT009	Adenosine Receptor
	Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias.		Adenosine Receptor
T10364	Arbutamine	GP 21213	Adrenergic Receptor
	Arbutamine (GP 21213) is a novel potent non-selective beta-adrenoceptor agonist with alpha-1-sympathomimetic activity.Arbutamine promotes cardiac stress and increases heart rate, cardiac contractility.Arbutamine can be u...		Adrenergic Receptor
T61316	HTS07545		NADPH
	HTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM).HTS07545 reduces the rate of hydrogen sulfide (H2S) decomposition.HTS07545 has been used in heart failure studies.		NADPH
T4S1518	Pseudoginsenoside RT1		Others
	Pseudoginsenoside RT1, isolated from the fruit of Randia siamensis, exhibits acute ichthyotoxic activity. Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontan...		Others
T0805	Quinapril hydrochloride	CI-906,PD-109452-2,Quinapril HCl	RAAS
	Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie...		RAAS
T0207	Ranolazine dihydrochloride	RS 43285,Ranolazine 2HCl	Calcium Channel , Sodium Channel , Autophagy
	Ranolazine dihydrochloride (Ranolazine 2HCl) , an antianginal agent, can treat arrhythmia via a novel mechanism of action (inhibition of the late phase of the inward sodium current), and do not affect blood pressure or h...		Calcium Channel , Sodium Channel , Autophagy
T3126	Bethanechol chloride	(±)-Bethanechol,Urecholine,Myocholine,Carbamyl-β-methylcholine chloride	AChR
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following ab...		AChR
TP1937L1	RFRP-1 (human) acetate(311309-25-8 free base)		Neuropeptide Y Receptor
	RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduc...		Neuropeptide Y Receptor
T1613	Hydralazine hydrochloride	Hydralazine HCl,Apresoline	MAO , HIF/HIF Prolyl-Hydroxylase
	Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release an...		MAO , HIF/HIF Prolyl-Hydroxylase
T1496	Amiodarone hydrochloride	Amiodar,Amiodarone HCl,Nexterone	Potassium Channel , Adrenergic Receptor , Autophagy
	Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM C...		Potassium Channel , Adrenergic Receptor , Autophagy
T50008	2,2-Dimethyl-5-(2,5-xylyloxy)valeramide	5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide	Others
	2,2-Dimethyl-5-(2,5-xylyloxy)valeramide (5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide) is a compound of the phenoxy family. It has been shown to have stimulatory effects on the nervous system, including increased neur...		Others
TP1369L	[Sar9,Met(O2)11]-Substance P acetate	[Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)	Neurokinin receptor
	[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (1...		Neurokinin receptor
T36008	Nebentan potassium
	Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan potassium inhibits [125I] endothelin-1 binding to cloned ...
T71800	Metoprolol HCl
	Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is...
T25237	Chloracyzine	Chloroacizine,Chloroacizin,Chlorazicine,Chloroacyzin
	Chloracyzine can produce a decrease in myocardial oxygen consumption accompanied by a reduction in coronary blood flow preceded by transient coronary dilatation. It produced an insignificant increase in arterial pressure...
TN1367	Alismol		Potassium Channel , Calcium Channel , PI3K
	Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.		Potassium Channel , Calcium Channel , PI3K
T60393	Clobutinol
	Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].